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Pentosan Equine injection 50ml

Special Price $410.00 $500.00
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Pentosan Equine Injection 50ml

Pentosan polysulfate sodium 250 mg/mL .

An aid in the treatment of non-infectious, inflammatory joint disease in horses.

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This item requires a prescription from your local veterinarian.
For help and information on prescription items please click here.

My Vet must have a valid prescription from your local vet for our licensed veterinarian before we can dispense it. We cannot prescribe medication for your pet as our veterinarian has not personally examined your pet, however we can dispense the medication.
To place your order, simply add this item to your cart and send your completed and signed prescription to My Vet, Unit 11, 16 Paerangi Place,Tauriko,Tauranga 3171
If your order is urgent you may fax your prescription to 07 9292864 or email it to [email protected] and then within 7 days post the original to¬†My Vet, Unit 11, 16 Paerangi Place,Tauriko,Tauranga 3171.

Once received, your order will be despatched to you.We are unable to accept returns of RVM (Restricted Veterinary Medicines)/Prescription items

Sodium pentosan polysulfate (PPS) is a linear polymer prepared from xylan, a complex hemicellulose extract of plant (Beechwood) origin.

PPS is one of the sulfated heparinoid compounds the heparin-like anti-coagulant effects have been reduced and the anti-inflammatory, fibrinolytic, and tissue trophic effects have been enhanced .

PENTOSAN EQUINE actively reverses the effects of osteoarthritis in the joints via a series of actions, including: Stimulating Chondrocyte Metabolism -resulting in increased production of proteoglycans and healthy cartilage matrix. PPS stimulates synovial fibroblasts to produce increased amounts of high molecular weight hyaluronic acid which results in an increased production of normally viscous joint fluid. Improving the fluid volume and consistency results in more effective joint lubrication and stabilisation, which limits further cartilage damage.

Anti-inflammatory Activity -PPS has an inhibitory action on all mediators of the 6 mL sterile Injection arachidonic acid cascade. PPS also inhibits the lysosomal catabolic enzymes hyaluronidase, histamine, cathepsin B, and polymorphonuclear elastase.

PPS exerts a specific inhibitory effect on mediators implicated in the degradation of cartilage matrix components, preserving the cartilage and preventing the release of the highly inflammatory mediators, thus relieving pain and inflammation. Fibrinolysis and Lipolysis - PPS is strongly fibrinolytic, stimulating the release of plasminogen activator, and promoting the dissolution of thrombi and fibrin deposits in synovial tissues and subchondral blood vessels PPS also mobilises lipids and cholesterol in synovial and subchondral blood vessels, which have been implicated in the pathogenesis of osteoarthritis in older animals

These effects combine to increase the prefusion to the joint, which stimulates cartilage healing and repair.

PENTOSAN EQUINE is a sophisticated approach to the long term management of osteoarthritis in horses.

PENTOSAN EQUINE is equally effective by both intramuscular and intra-articular injection. Unlike traditional treatments, the unique effects of PENTOSAN EQUINE promote healing and the restoration of a healthy joint, in addition to having a safe anti- inflammatory effect.

Pentosan Equine injection should be administered by i/m or i/a injection at a dosage of 3mg/kg b.w.(6mL vial/500kg horse) at 5-7 day intervals for 4 injections.

For maximum effect tissues should be exposed to the drug over an extended period of time. In approximately 80% of accurately diagnosed conditions a marked improvement will be noted after the second injection.

Improvement for up to 6 months following a course of 4 injections can be expected and a lot of competition horses stay on a monthly injection protocol

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